As we discussed in the previous blog post, disruption of the single cell intestinal barrier which separates the immune layer from the contents of the intestinal lumen is a known component to the onset of autoimmunity.  A leaky gut barrier allows highly inflammatory and immune activating bacterial particles called lipopolysaccharides (LPS) to flood into the […]

In the last several blogs we looked at the research on the human microbiome which corresponds to the onset of the many diseases that become more prevalent with age.  Keep in mind “with age” does not mean after the age of 60-70 but rather gradually beginning between age 30-40. This shift is hallmarked by the […]

In the previous blogs we discussed the interesting work on altering the microbiome with fecal medical transplant (FMT) to correct inflammation, inflammatory related disease, diabetes, and other chronic health problems.  The results are pretty dramatic.  The problem is that FMT requires endoscopy/colonoscopy, cost and further FDA approval.  Right now it is only approved to treat […]

A parallel observation occurring as humans age and develop the common age related diseases is that the intestinal microbiome shifts to a different population.  That begs the question whether these are simply unrelated changes or does one contribute to the other.  In the previous blog I discussed the interesting study which found that fecal medical […]