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Too much appeasing of a sweet tooth has been associated with an increased risk of developing autoimmunity.  While higher sugar consumption may do so, artificial sweeteners appear to increase the risk similarly.  This is a significant concern as either sugars or artificial sweeteners are added to almost all processed foods. Humans have 3 primary taste […]

When a Sweet Tooth Helps Trigger Autoimmunity

February 2, 2023

This title may sound like some form of double talk but it is a reality.  I had a stark example of this concept last weekend traveling to Easton Maryland for our annual goose hunt with my grandson.  Traveling the 185 miles up the Virginia and Maryland Eastern Shore I traveled through this large expanse of […]

When “Non-food” Foods Trigger Autoimmunity

January 26, 2023

In the previous blogs we have discussed the role of the “exposome” which are the environmental factors we are exposed to that may contribute to autoimmunity.  One of the more common and important factors is diet/food.  This process involves an immune reaction against a food particle such as a peptide that then spreads to attacking […]

When Food Triggers Autoimmunity

January 10, 2023

As we discussed in the previous blog post, disruption of the single cell intestinal barrier which separates the immune layer from the contents of the intestinal lumen is a known component to the onset of autoimmunity.  A leaky gut barrier allows highly inflammatory and immune activating bacterial particles called lipopolysaccharides (LPS) to flood into the […]

Dysbiosis and Autoimmunity

December 27, 2022

The first line of defense in the body against invaders that can abnormally activate the immune system are our physical barriers such as the skin and intestinal barrier.  The intestinal barrier is especially important for multiple reasons: If this barrier is “breached” the body is flooded with factors that activate inflammation and antibody production to […]

Autoimmunity and Leaky Gut

December 8, 2022

One of a Few Common Chronic Diseases That We Are Now More Likely to Face Advances in research have helped the U.S. enjoy decreasing rates of several chronic diseases over the past 3 decades.  Autoimmune disease has been a notable exception to this trend increasing rather dramatically.  This trend has been broad with sharp increases […]

Autoimmunity

December 1, 2022

In the last several blogs we looked at the research on the human microbiome which corresponds to the onset of the many diseases that become more prevalent with age.  Keep in mind “with age” does not mean after the age of 60-70 but rather gradually beginning between age 30-40. This shift is hallmarked by the […]

Why Does Our Microbiome Undergo an Unhealthy Shift with Age?

November 17, 2022

In the previous blogs we discussed the interesting work on altering the microbiome with fecal medical transplant (FMT) to correct inflammation, inflammatory related disease, diabetes, and other chronic health problems.  The results are pretty dramatic.  The problem is that FMT requires endoscopy/colonoscopy, cost and further FDA approval.  Right now it is only approved to treat […]

Can the Microbiome Changes with Age and Disease Be Corrected With Probiotics?

November 1, 2022

A parallel observation occurring as humans age and develop the common age related diseases is that the intestinal microbiome shifts to a different population.  That begs the question whether these are simply unrelated changes or does one contribute to the other.  In the previous blog I discussed the interesting study which found that fecal medical […]

Who Are the Superstars in the Human Microbiome?

October 20, 2022

Day two of the conference I discussed in the last blog concentrated on the microbiome which is this enormous population of micro-organisms such as bacteria that live in and on us.  The microbiome has been known to exist for many decades but was poorly understood until heavily researched in the last 20 years.  One of […]

The Microbiome as a Key in Health and Disease

October 13, 2022